General Cell Based Assays
Revvity Health Sciences Inc HTRF Human Total IκKβ Detection Kit, 500 Assay Points
HTRF Human Total IκKβ Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human H232 STING Binding Kit, 100,000 Assay Points
HTRF Human H232 STING Binding Kit, 100,000 Assay Points
Eurofins Discoverx PathHunter TrkB-P75 Bioassay Kit, 10-Plate. (93-0530Y3-00076)
The PathHunter TrkB-P75 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. BDNF) induced dimerization of TrkB-P75 receptors. This product uses EFC technology. The included cell line overexpresses ProLink-tagged TrkB and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, P75. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. Upon ligand-induced dimerization of TrkB-P75, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Revvity Health Sciences Inc HTRF Human Perforin-1 Detection Kit, 500 Assay Points
HTRF Human Perforin-1 Detection Kit, 500 Assay Points
Eurofins Discoverx PathHunter eXpress mUTR2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0525E2MCP0L)
The PathHunter mUTR2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. urotensin II) based activation of mUTR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mUTR2 and EA-tagged β-Arrestin-2. Activation of mUTR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mGLP1R CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0478E2MCP0L)
The PathHunter mGLP1R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. exendin-4) based activation of mGLP1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGLP1R and EA-tagged β-Arrestin-2. Activation of mGLP1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCRHR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0473E2MCP0M)
The PathHunter mCRHR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CRH, sauvagine) based activation of mCRHR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCRHR1 and EA-tagged β-Arrestin-2. Activation of mCRHR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Total AKT1 Detection Kit, 500 Assay Points
HTRF Human Total AKT1 Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human Total SMAD1 Detection Kit, 500 Assay Points
HTRF Human Total SMAD1 Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Phospho-NDRG1 (Thr346) Detection Kit, 10,000 Assay Points
HTRF Phospho-NDRG1 (Thr346) Detection Kit, 10,000 Assay Points
Eurofins Discoverx PathHunter eXpress OPRM1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0213E2CP0L)
The PathHunter OPRM1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. met 5-enkephalin) based activation of OPRM1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRM1 and EA-tagged β-Arrestin-2. Activation of OPRM1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress F2RL1 (PAR2; GPR11) HEK 293 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0235E1CP0L)
The PathHunter F2RL1 (PAR2; GPR11) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. proteases, SLIGRL) based activation of F2RL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged F2RL1 and EA-tagged β-Arrestin-2. Activation of F2RL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
ILEX LIFE SCIENCES LLC BLYSCAN SGAG ISO/CONC REAGENTS
Biocolor Blyscan Glycosaminoglycan (sGAG) Isolation & Concentration Pack (100 samples). DESCRIPTION: Isolation & Concentration reagents for use with Blyscan Glycosaminoglycan Assay. Blyscan Glycosaminoglycan Assay is a quantitative colorimetric dye-binding method for analysis of sulfated proteoglycans and glycosaminoglycans (sGAG). It can be used to measure total sGAG content and can also to determine the O- and N-sulfated GAG ratio within test samples. The assay uses 1,9-dimethylmethylene blue dye employed under conditions that provide a specific label for the sulfated polysaccharide component of proteoglycans or the protein free sulfated glycosaminoglycan chains. APPLICATIONS: Cell culture derived material, soluble sGAGs from fluids (ex. synovial fluid, urine), fibrous and hyaline cartilages, tissues (ex. arteries, heart, lung, skin, tumors). Soluble sGAGs may be assayed directly, solid materials will require a preliminary papain extraction.
Eurofins Discoverx cAMP Hunter™ Human Apelin (APJ Receptor) Gi cAMP Cell-Based Assay Kit (CHO-K1)
The cAMP Hunter™ Human Apelin (APJ Receptor) Gi Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure AGTRL1 (GPCR) activity via decreased levels of intracellular cAMP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.